Structure-activity relationships (SAR) analysis is crucial in drug discovery. By systematically modifying the chemical structure of a lead compound and quantifying the resulting biological activity, researchers determine the key structural features responsible for desired effects. This understanding

Pharmacological profiling represents a crucial/essential/fundamental step in the development/synthesis/design of novel drug candidates. This process involves/encompasses/includes a comprehensive/thorough/systematic assessment of a drug's pharmacological/therapeutic/biochemical properties, aiming to